Spastic paraplegia four (SPG4; generally known as SPAST-HSP) is characterised by insidiously progressive bilateral decreased-limb gait spasticity. A lot more than fifty% of impacted individuals have some weak point during the legs and impaired vibration sense at the ankles.????? ??? ????? ???? ????.????? ???? ??? ??? ??? ???? ?????.??? ?? ??: ????